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The Homotetrameric Phosphoseryl-tRNA Synthetase from Methanosarcina mazei Exhibits Half-of-the-sites Activity

Synthesis of cysteinyl-tRNA(Cys) in methanogenic archaea proceeds by a two-step pathway in which tRNA(Cys) is first aminoacylated with phosphoserine by phosphoseryl-tRNA synthetase (SepRS). Characterization of SepRS from the mesophile Methanosarcina mazei by gel filtration and nondenaturing mass spe...

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Bibliografske podrobnosti
Main Authors: Hauenstein, Scott I., Hou, Ya-Ming, Perona, John J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494909/
https://ncbi.nlm.nih.gov/pubmed/18559342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801838200
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