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Efficient and accurate bypass of N(2)-(1-carboxyethyl)-2′-deoxyguanosine by DinB DNA polymerase in vitro and in vivo
DinB, a Y-family DNA polymerase, is conserved among all domains of life; however, its endogenous substrates have not been identified. DinB is known to synthesize accurately across a number of N(2)-dG lesions. Methylglyoxal (MG) is a common byproduct of the ubiquitous glycolysis pathway and induces t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2438377/ https://ncbi.nlm.nih.gov/pubmed/18562283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711546105 |
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