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Stereospecific Synthesis and Characterization of Oligodeoxyribonucleotides Containing an N(2)-(1-Carboxyethyl)-2′-deoxyguanosine
Methylglyoxal is a highly reactive α-ketoaldehyde that is produced endogenously and present in the environment and foods. It can modify DNA and proteins to form advanced glycation end products (AGEs). Emerging evidence has shown that N(2)-(1-carboxyethyl)-2′-deoxyguanosine (N(2)-CEdG) is a major mar...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169888/ https://ncbi.nlm.nih.gov/pubmed/17877341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja072130e |
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