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Synthesis and Thermodynamic Studies of Oligodeoxyribonucleotides Containing Tandem Lesions of Thymidine Glycol and 8-oxo-2′-Deoxyguanosine

Thymidine glycol (Tg), which is also known as 5,6-dihydroxy-5,6-dihydrothymidine, and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) are two major types of DNA damage products induced by reactive oxygen species (ROS). Here we report the synthesis of oligodeoxyribonucleotides (ODNs) containing both Tg...

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Dettagli Bibliografici
Autori principali: Wang, Yuesong, Wang, Yinsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533691/
https://ncbi.nlm.nih.gov/pubmed/16780363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060032l
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