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Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs
Mechanisms to safely eliminate amyloids and preamyloid oligomers associated with many devastating diseases are urgently needed. Biophysical principles dictate that small molecules are unlikely to perturb large intermolecular protein–protein interfaces, let alone extraordinarily stable amyloid interf...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2438221/ https://ncbi.nlm.nih.gov/pubmed/18480256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801934105 |
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