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Structural insights into a yeast prion illuminate nucleation and strain diversity
Self-perpetuating changes in the conformations of amyloidogenic proteins play vital roles in normal biology and disease. Despite intense research, amyloid architecture and conformational conversion remain poorly understood. Amyloid conformers of Sup35 are the molecular embodiment of the yeast prion...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1405905/ https://ncbi.nlm.nih.gov/pubmed/15944694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03679 |
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