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Structural insights into a yeast prion illuminate nucleation and strain diversity

Self-perpetuating changes in the conformations of amyloidogenic proteins play vital roles in normal biology and disease. Despite intense research, amyloid architecture and conformational conversion remain poorly understood. Amyloid conformers of Sup35 are the molecular embodiment of the yeast prion...

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Bibliografiska uppgifter
Huvudupphovsmän: Krishnan, Rajaraman, Lindquist, Susan L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1405905/
https://ncbi.nlm.nih.gov/pubmed/15944694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03679
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