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Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI(+)]

Prions are proteins that can access multiple conformations, at least one of which is β-sheet rich, infectious and self-perpetuating in nature. These infectious proteins show several remarkable biological activities, including the ability to form multiple infectious prion conformations, also known as...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Tessier, Peter M, Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502417/
https://ncbi.nlm.nih.gov/pubmed/19491937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1617
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