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[PSI(+)] Prion Variant Establishment in Yeast

Differences in the clinical pathology of mammalian prion diseases reflect distinct heritable conformations of aggregated PrP proteins, called prion strains. Here, using the yeast [PSI(+)] prion, we examine the de novo establishment of prion strains (called variants in yeast). The [PSI(+)] prion prot...

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Detalhes bibliográficos
Main Authors: Sharma, Jaya, Liebman, Susan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543502/
https://ncbi.nlm.nih.gov/pubmed/22998111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12024
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