Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity

Structural conversion of one given protein sequence into different amyloid states, resulting in distinct phenotypes, is one of the most intriguing phenomena of protein biology. Despite great efforts the structural origin of prion diversity remains elusive, mainly because amyloids are insoluble yet n...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Reymer, Anna, Frederick, Kendra K., Rocha, Sandra, Beke-Somfai, Tamás, Kitts, Catherine C., Lindquist, Susan, Nordén, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260602/
https://ncbi.nlm.nih.gov/pubmed/25404291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415663111
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