Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity

Structural conversion of one given protein sequence into different amyloid states, resulting in distinct phenotypes, is one of the most intriguing phenomena of protein biology. Despite great efforts the structural origin of prion diversity remains elusive, mainly because amyloids are insoluble yet n...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Reymer, Anna, Frederick, Kendra K., Rocha, Sandra, Beke-Somfai, Tamás, Kitts, Catherine C., Lindquist, Susan, Nordén, Bengt
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260602/
https://ncbi.nlm.nih.gov/pubmed/25404291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415663111
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