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Michler’s hydrol blue elucidates structural differences in prion strains

Yeast prions provide self-templating protein-based mechanisms of inheritance whose conformational changes lead to the acquisition of diverse new phenotypes. The best studied of these is the prion domain (NM) of Sup35, which forms an amyloid that can adopt several distinct conformations (strains) tha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xiao, Yiling, Rocha, Sandra, Kitts, Catherine C., Reymer, Anna, Beke-Somfai, Tamás, Frederick, Kendra K., Nordén, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703575/
https://ncbi.nlm.nih.gov/pubmed/33168711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001732117
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