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Rate of hydrolysis in ATP synthase is fine-tuned by α-subunit motif controlling active site conformation

Computer-designed artificial enzymes will require precise understanding of how conformation of active sites may control barrier heights of key transition states, including dependence on structure and dynamics at larger molecular scale. F(o)F(1) ATP synthase is interesting as a model system: a delica...

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Hlavní autoři: Beke-Somfai, Tamás, Lincoln, Per, Nordén, Bengt
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568300/
https://ncbi.nlm.nih.gov/pubmed/23345443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214741110
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