Michler’s hydrol blue elucidates structural differences in prion strains

Yeast prions provide self-templating protein-based mechanisms of inheritance whose conformational changes lead to the acquisition of diverse new phenotypes. The best studied of these is the prion domain (NM) of Sup35, which forms an amyloid that can adopt several distinct conformations (strains) tha...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Xiao, Yiling, Rocha, Sandra, Kitts, Catherine C., Reymer, Anna, Beke-Somfai, Tamás, Frederick, Kendra K., Nordén, Bengt
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703575/
https://ncbi.nlm.nih.gov/pubmed/33168711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001732117
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