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Topoisomerase levels determine chemotherapy response in vitro and in vivo
Topoisomerase poisons are chemotherapeutic agents that are used extensively for treating human malignancies. These drugs can be highly effective, yet tumors are frequently refractory to treatment or become resistant upon tumor relapse. Using a pool-based RNAi screening approach and a well characteri...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435590/ https://ncbi.nlm.nih.gov/pubmed/18574145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803513105 |
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