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Synthetic Intron Improves Transduction Efficiency of Trans-Splicing Adeno-Associated Viral Vectors

Trans-splicing adeno-associated viral (AAV) vectors hold great promise in many gene therapy applications. We have shown that rational selection of the gene-splitting site in a therapeutic target gene can lead to extremely efficient trans-splicing vectors [Lai, Y., Yue, Y., Liu, M., Ghosh, A., Engelh...

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Detaylı Bibliyografya
Asıl Yazarlar: LAI, YI, YUE, YONGPING, LIU, MINGJU, DUAN, DONGSHENG
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431463/
https://ncbi.nlm.nih.gov/pubmed/17007565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2006.17.ft-246
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