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Binding and Catalytic Contributions to Site Recognition by Flp Recombinase
Flp catalyzes site-specific recombination in a highly sequence-specific manner despite making few direct contacts to the bases within its binding site. Sequence discrimination could take place in the binding and/or the catalytic steps. In this study, we independently measure the binding affinity and...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431069/ https://ncbi.nlm.nih.gov/pubmed/18276592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800106200 |
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