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Binding and Catalytic Contributions to Site Recognition by Flp Recombinase

Flp catalyzes site-specific recombination in a highly sequence-specific manner despite making few direct contacts to the bases within its binding site. Sequence discrimination could take place in the binding and/or the catalytic steps. In this study, we independently measure the binding affinity and...

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Detalhes bibliográficos
Main Authors: Whiteson, Katrine L., Rice, Phoebe A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431069/
https://ncbi.nlm.nih.gov/pubmed/18276592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800106200
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