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Amino Acid Residues That Confer High Selectivity of the α6 Nicotinic Acetylcholine Receptor Subunit to α-Conotoxin MII[S4A,E11A,L15A]
Nicotinic acetylcholine receptors (nAChRs) containing α3 and β2 subunits are found in autonomic ganglia and mediate ganglionic transmission. The closely related α6 nAChR subtype is found in the central nervous system where changes in its level of expression are observed in Parkinson's disease....
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431060/ https://ncbi.nlm.nih.gov/pubmed/18299323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710288200 |
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