α-Conotoxin PIA Is Selective for α6 Subunit-Containing Nicotinic Acetylcholine Receptors

Until now, there have been no antagonists to discriminate between heteromeric nicotinic acetylcholine receptors (nAChRs) containing the very closely related α6 and α3 subunits. nAChRs containing α3, α4, or α6 subunits in combination with β2, occasionally β4, and sometimes β3 or α5 subunits, are thou...

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Pubblicato in:J Neurosci
Autori principali: Dowell, Cheryl, Olivera, Baldomero M., Garrett, James E., Staheli, Sarah T., Watkins, Maren, Kuryatov, Alexander, Yoshikami, Doju, Lindstrom, Jon M., McIntosh, J. Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740366/
https://ncbi.nlm.nih.gov/pubmed/13679412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-24-08445.2003
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