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Amino Acid Residues That Confer High Selectivity of the α6 Nicotinic Acetylcholine Receptor Subunit to α-Conotoxin MII[S4A,E11A,L15A]

Nicotinic acetylcholine receptors (nAChRs) containing α3 and β2 subunits are found in autonomic ganglia and mediate ganglionic transmission. The closely related α6 nAChR subtype is found in the central nervous system where changes in its level of expression are observed in Parkinson's disease....

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Détails bibliographiques
Auteurs principaux: Azam, Layla, Yoshikami, Doju, McIntosh, J. Michael
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431060/
https://ncbi.nlm.nih.gov/pubmed/18299323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710288200
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