Загрузка...
Mycophenolic Acid Activation of p53 Requires Ribosomal Proteins L5 and L11
Mycophenolate mofetil (MMF), a prodrug of mycophenolic acid (MPA), is widely used as an immunosuppressive agent. MPA selectively inhibits inosine monophosphate dehydrogenase (IMPDH), a rate-limiting enzyme for the de novo synthesis of guanine nucleotides, leading to depletion of the guanine nucleoti...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2008
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430998/ https://ncbi.nlm.nih.gov/pubmed/18305114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801387200 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|