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The Case for 8, 5’-Cyclopurine-2’-Deoxynucleosides as Endogenous DNA Lesions That Cause Neurodegeneration in Xeroderma Pigmentosum
Patients with the genetic disease xeroderma pigmentosum (XP) lack the capacity to carry out a specific type of DNA repair process called nucleotide excision repair (NER). The NER pathway plays a critical role in the repair of DNA damage resulting from UV radiation. A subset of XP patients develop a...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430073/ https://ncbi.nlm.nih.gov/pubmed/17184928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.10.025 |
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