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The Stereochemical Course of 4-Hydroxy-2-nonenal Metabolism by Glutathione S-Transferases
4-Hydroxy-2-nonenal (HNE) is a toxic aldehyde generated during lipid peroxidation and has been implicated in a variety of pathological states associated with oxidative stress. Glutathione S-transferase (GST) A4-4 is recognized as one of the predominant enzymes responsible for the metabolism of HNE....
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423235/ https://ncbi.nlm.nih.gov/pubmed/18424441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801725200 |
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