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Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N(6)-ethenoadenine and hypoxanthine but not of 3,N(4)-ethenocytosine or 8-oxoguanine

It has previously been reported that 1,N(6)-ethenoadenine (ɛA), deaminated adenine (hypoxanthine, Hx), and 7,8-dihydro-8-oxoguanine (8-oxoG), but not 3,N(4)-ethenocytosine (ɛC), are released from DNA in vitro by the DNA repair enzyme alkylpurine-DNA-N-glycosylase (APNG). To assess the potential cont...

詳細記述

保存先:
書誌詳細
主要な著者: Hang, B., Singer, B., Margison, G. P., Elder, R. H.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC24230/
https://ncbi.nlm.nih.gov/pubmed/9371767
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