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Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylase

1,N(6)-ethenoadenine adducts (εA) are formed by known environmental carcinogens and found to be removed by human alkylpurine-DNA N-glycosylase (APNG). 1,N(6)-ethanoadenine (ΕA) adducts differ from εA by change of a double bond to a single bond in the 5-member exocyclic ring and are formed by chloroe...

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Bibliografische gegevens
Hoofdauteurs: Guliaev, Anton B., Hang, Bo, Singer, B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137416/
https://ncbi.nlm.nih.gov/pubmed/12202763
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