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A link between protein structure and enzyme catalyzed hydrogen tunneling

We present evidence that the size of an active site side chain may modulate the degree of hydrogen tunneling in an enzyme-catalyzed reaction. Primary and secondary k(H)/k(T) and k(D)/k(T) kinetic isotope effects have been measured for the oxidation of benzyl alcohol catalyzed by horse liver alcohol...

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Bibliografski detalji
Glavni autori: Bahnson, Brian J., Colby, Thomas D., Chin, Jodie K., Goldstein, Barry M., Klinman, Judith P.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24218/
https://ncbi.nlm.nih.gov/pubmed/9371755
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