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Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1

This study examines the impact of a series of mutations at position 553 on the kinetic and structural properties of soybean lipoxygenase-1 (SLO-1). The previously uncharacterized mutants reported herein are I553L, I553V, and I553G. High-resolution x-ray studies of these mutants, together with the ea...

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Bibliografske podrobnosti
Main Authors: Meyer, Matthew P., Tomchick, Diana R., Klinman, Judith P.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234106/
https://ncbi.nlm.nih.gov/pubmed/18216254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710643105
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