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Linking protein structure and dynamics to catalysis: the role of hydrogen tunnelling

Early studies of enzyme-catalysed hydride transfer reactions indicated kinetic anomalies that were initially interpreted in the context of a ‘tunnelling correction’. An alternate model for tunnelling emerged following studies of the hydrogen atom transfer catalysed by the enzyme soybean lipoxygenase...

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Autor principal: Klinman, Judith P
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1647309/
https://ncbi.nlm.nih.gov/pubmed/16873120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2006.1870
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