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Structural and Functional Consequences of Tyrosine Phosphorylation in the LRP1 Cytoplasmic Domain

The cytoplasmic domain of LRP1 contains two NPXY motifs that have been shown to interact with signaling proteins. In previous work, we showed that Tyr(4507) in the distal NPXY motif is phosphorylated by v-Src, whereas denaturation of the protein was required for phosphorylation of Tyr(4473) in the m...

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Autors principals: Betts, Gina N., van der Geer, Peter, Komives, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414285/
https://ncbi.nlm.nih.gov/pubmed/18381291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709514200
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