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Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases
Constitutive activation of receptor tyrosine kinases (RTKs) is a frequent event in human cancer cells. Activating mutations in Fms-like tyrosine kinase 3 (FLT-3), notably, internal tandem duplications in the juxtamembrane domain (FLT-3 ITD), have been causally linked to acute myeloid leukemia. As we...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084288/ https://ncbi.nlm.nih.gov/pubmed/15831474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3690-3703.2005 |
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