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Liver Kinase B1 Expression Promotes Phosphatase Activity and Abrogation of Receptor Tyrosine Kinase Phosphorylation in Human Cancer Cells
Aberrant receptor tyrosine kinase phosphorylation (pRTK) has been associated with diverse pathological conditions, including human neoplasms. In lung cancer, frequent liver kinase B1 (LKB1) mutations correlate with tumor progression, but potential links with pRTK remain unknown. Heightened and susta...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894343/ https://ncbi.nlm.nih.gov/pubmed/24285539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500934 |
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