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Liver Kinase B1 Expression Promotes Phosphatase Activity and Abrogation of Receptor Tyrosine Kinase Phosphorylation in Human Cancer Cells

Aberrant receptor tyrosine kinase phosphorylation (pRTK) has been associated with diverse pathological conditions, including human neoplasms. In lung cancer, frequent liver kinase B1 (LKB1) mutations correlate with tumor progression, but potential links with pRTK remain unknown. Heightened and susta...

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Detalhes bibliográficos
Main Authors: Okon, Imoh S., Coughlan, Kathleen A., Zou, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894343/
https://ncbi.nlm.nih.gov/pubmed/24285539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500934
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