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Altered Dimer Interface Decreases Stability in an Amyloidogenic Protein

Amyloidoses are devastating and currently incurable diseases in which the process of amyloid formation causes fatal cellular and organ damage. The molecular mechanisms underlying amyloidoses are not well known. In this study, we address the structural basis of immunoglobulin light chain amyloidosis,...

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Detalhes bibliográficos
Main Authors: Baden, Elizabeth M., Owen, Barbara A. L., Peterson, Francis C., Volkman, Brian F., Ramirez-Alvarado, Marina, Thompson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414275/
https://ncbi.nlm.nih.gov/pubmed/18400753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705347200
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