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Altered Dimer Interface Decreases Stability in an Amyloidogenic Protein

Amyloidoses are devastating and currently incurable diseases in which the process of amyloid formation causes fatal cellular and organ damage. The molecular mechanisms underlying amyloidoses are not well known. In this study, we address the structural basis of immunoglobulin light chain amyloidosis,...

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Main Authors: Baden, Elizabeth M., Owen, Barbara A. L., Peterson, Francis C., Volkman, Brian F., Ramirez-Alvarado, Marina, Thompson, James R.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414275/
https://ncbi.nlm.nih.gov/pubmed/18400753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705347200
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