Altered Dimer Interface Decreases Stability in an Amyloidogenic Protein

Amyloidoses are devastating and currently incurable diseases in which the process of amyloid formation causes fatal cellular and organ damage. The molecular mechanisms underlying amyloidoses are not well known. In this study, we address the structural basis of immunoglobulin light chain amyloidosis,...

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Bibliographic Details
Main Authors: Baden, Elizabeth M., Owen, Barbara A. L., Peterson, Francis C., Volkman, Brian F., Ramirez-Alvarado, Marina, Thompson, James R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414275/
https://ncbi.nlm.nih.gov/pubmed/18400753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705347200
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