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Freeze Drying of Peptide Drugs Self-Associated with Long-Circulating, Biocompatible and Biodegradable Sterically Stabilized Phospholipid Nanomicelles
The purpose of this study was to determine optimal lipid concentration range for lyophilization of sterically stabilized phospholipid nanomicelles (SSM) and the freeze drying feasibility of self-associated therapeutic peptide-SSM assemblies. SSM at 5 to 20 mM 1,2-distearoyl-sn-glycero-3-phosphoethan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413132/ https://ncbi.nlm.nih.gov/pubmed/18289811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.01.014 |
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