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Freeze Drying of Peptide Drugs Self-Associated with Long-Circulating, Biocompatible and Biodegradable Sterically Stabilized Phospholipid Nanomicelles
The purpose of this study was to determine optimal lipid concentration range for lyophilization of sterically stabilized phospholipid nanomicelles (SSM) and the freeze drying feasibility of self-associated therapeutic peptide-SSM assemblies. SSM at 5 to 20 mM 1,2-distearoyl-sn-glycero-3-phosphoethan...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413132/ https://ncbi.nlm.nih.gov/pubmed/18289811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.01.014 |
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