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Freeze Drying of Peptide Drugs Self-Associated with Long-Circulating, Biocompatible and Biodegradable Sterically Stabilized Phospholipid Nanomicelles

The purpose of this study was to determine optimal lipid concentration range for lyophilization of sterically stabilized phospholipid nanomicelles (SSM) and the freeze drying feasibility of self-associated therapeutic peptide-SSM assemblies. SSM at 5 to 20 mM 1,2-distearoyl-sn-glycero-3-phosphoethan...

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Sonraí Bibleagrafaíochta
Main Authors: Lim, Sok Bee, Rubinstein, Israel, Önyüksel, Hayat
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413132/
https://ncbi.nlm.nih.gov/pubmed/18289811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.01.014
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