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Freeze Drying of Peptide Drugs Self-Associated with Long-Circulating, Biocompatible and Biodegradable Sterically Stabilized Phospholipid Nanomicelles

The purpose of this study was to determine optimal lipid concentration range for lyophilization of sterically stabilized phospholipid nanomicelles (SSM) and the freeze drying feasibility of self-associated therapeutic peptide-SSM assemblies. SSM at 5 to 20 mM 1,2-distearoyl-sn-glycero-3-phosphoethan...

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Hlavní autoři: Lim, Sok Bee, Rubinstein, Israel, Önyüksel, Hayat
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413132/
https://ncbi.nlm.nih.gov/pubmed/18289811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2008.01.014
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