Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

Sterol regulatory element binding proteins (SREBPs) enhance transcription of genes encoding enzymes of cholesterol and fatty acid biosynthesis and uptake. In the current experiments, we observed a decline in the mRNA encoding one SREBP isoform, SREBP-1c, in the livers of rats that were rendered diab...

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Hlavní autoři: Shimomura, Iichiro, Bashmakov, Yuriy, Ikemoto, Shinji, Horton, Jay D., Brown, Michael S., Goldstein, Joseph L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1999
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24120/
https://ncbi.nlm.nih.gov/pubmed/10570128
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