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Nck adaptor proteins control the organization of neuronal circuits important for walking

The intracellular signaling targets used by mammalian axon guidance receptors to organize the nervous system in vivo are unclear. The Nck1 and Nck2 SH2/SH3 adaptors (collectively Nck) can couple phosphotyrosine (pTyr) signals to reorganization of the actin cytoskeleton and are therefore candidates f...

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Detalhes bibliográficos
Main Authors: Fawcett, James P., Georgiou, John, Ruston, Julie, Bladt, Friedhelm, Sherman, Andrew, Warner, Neil, Saab, Bechara J., Scott, Rizaldy, Roder, John C., Pawson, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409251/
https://ncbi.nlm.nih.gov/pubmed/18093944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710316105
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