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Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire
The size and sensitivity of the T-cell repertoire governs the effectiveness of immune responses against invading pathogens. Both are modulated by T-cell receptor (TCR) activity through molecular mechanisms, which remain unclear. Here, we provide genetic evidence that the SH2/SH3 domain containing pr...
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| Main Authors: | , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932578/ https://ncbi.nlm.nih.gov/pubmed/20709959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009743107 |
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