The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network

Mammalian Nck1 and Nck2 are closely related adaptor proteins that possess three SH3 domains, followed by an SH2 domain, and are implicated in coupling phosphotyrosine signals to polypeptides that regulate the actin cytoskeleton. However, the in vivo functions of Nck1 and Nck2 have not been defined....

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Detalhes bibliográficos
Main Authors: Bladt, Friedhelm, Aippersbach, Elke, Gelkop, Sigal, Strasser, Geraldine A., Nash, Piers, Tafuri, Anna, Gertler, Frank B., Pawson, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164855/
https://ncbi.nlm.nih.gov/pubmed/12808099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4586-4597.2003
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