The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network

Mammalian Nck1 and Nck2 are closely related adaptor proteins that possess three SH3 domains, followed by an SH2 domain, and are implicated in coupling phosphotyrosine signals to polypeptides that regulate the actin cytoskeleton. However, the in vivo functions of Nck1 and Nck2 have not been defined....

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Autors principals: Bladt, Friedhelm, Aippersbach, Elke, Gelkop, Sigal, Strasser, Geraldine A., Nash, Piers, Tafuri, Anna, Gertler, Frank B., Pawson, Tony
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164855/
https://ncbi.nlm.nih.gov/pubmed/12808099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4586-4597.2003
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