The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network

Mammalian Nck1 and Nck2 are closely related adaptor proteins that possess three SH3 domains, followed by an SH2 domain, and are implicated in coupling phosphotyrosine signals to polypeptides that regulate the actin cytoskeleton. However, the in vivo functions of Nck1 and Nck2 have not been defined....

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Autori principali: Bladt, Friedhelm, Aippersbach, Elke, Gelkop, Sigal, Strasser, Geraldine A., Nash, Piers, Tafuri, Anna, Gertler, Frank B., Pawson, Tony
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164855/
https://ncbi.nlm.nih.gov/pubmed/12808099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4586-4597.2003
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