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Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons

Tetanus neurotoxin causes the spastic paralysis of tetanus by blocking neurotransmitter release at inhibitory synapses of the spinal cord. This is due to the penetration of the toxin inside the neuronal cytosol where it cleaves specifically VAMP/synaptobrevin, an essential component of the neuroexoc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Matteoli, Michela, Verderio, Claudia, Rossetto, Ornella, Iezzi, Numa, Coco, Silvia, Schiavo, Giampietro, Montecucco, Cesare
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences of the USA 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC24089/
https://ncbi.nlm.nih.gov/pubmed/8917587
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