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Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons

Tetanus neurotoxin causes the spastic paralysis of tetanus by blocking neurotransmitter release at inhibitory synapses of the spinal cord. This is due to the penetration of the toxin inside the neuronal cytosol where it cleaves specifically VAMP/synaptobrevin, an essential component of the neuroexoc...

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Bibliografische gegevens
Hoofdauteurs: Matteoli, Michela, Verderio, Claudia, Rossetto, Ornella, Iezzi, Numa, Coco, Silvia, Schiavo, Giampietro, Montecucco, Cesare
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24089/
https://ncbi.nlm.nih.gov/pubmed/8917587
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