Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons
Tetanus neurotoxin causes the spastic paralysis of tetanus by blocking neurotransmitter release at inhibitory synapses of the spinal cord. This is due to the penetration of the toxin inside the neuronal cytosol where it cleaves specifically VAMP/synaptobrevin, an essential component of the neuroexoc...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.13310 |
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