Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses.

The clostridial neurotoxins responsible for tetanus and botulism are proteins consisting of three domains endowed with different functions: neurospecific binding, membrane translocation and proteolysis for specific components of the neuroexocytosis apparatus. Tetanus neurotoxin (TeNT) binds to the p...

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Bibliografiske detaljer
Main Authors: Pellizzari, R, Rossetto, O, Schiavo, G, Montecucco, C
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692495/
https://ncbi.nlm.nih.gov/pubmed/10212474
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