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Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses.

The clostridial neurotoxins responsible for tetanus and botulism are proteins consisting of three domains endowed with different functions: neurospecific binding, membrane translocation and proteolysis for specific components of the neuroexocytosis apparatus. Tetanus neurotoxin (TeNT) binds to the p...

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Detalles Bibliográficos
Main Authors: Pellizzari, R, Rossetto, O, Schiavo, G, Montecucco, C
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692495/
https://ncbi.nlm.nih.gov/pubmed/10212474
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