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Metal substitution of tetanus neurotoxin.

Tetanus neurotoxin was depleted of its catalytic Zn2+ ion, and the apotoxin was reconstituted with different transition metal ions. The Mn2+- and Co2+-tetanus neurotoxins are highly active in the proteolysis of vesicle-associated membrane protein/synaptobrevin, the natural substrate of this toxin, w...

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Detalhes bibliográficos
Main Authors: Tonello, F, Schiavo, G, Montecucco, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218219/
https://ncbi.nlm.nih.gov/pubmed/9065770
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