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Hypothalamic malonyl-CoA as a mediator of feeding behavior
Previous studies showed that i.p. administration of C75, a potent inhibitor of fatty acid synthase (FAS), blocked fasting-induced up-regulation of orexigenic neuropeptides and down-regulation of anorexigenic neuropeptides in the hypothalami of mice. As a result, food intake and body weight were dras...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC240668/ https://ncbi.nlm.nih.gov/pubmed/14532332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834402100 |
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