Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a

Hypothalamic fatty acid metabolism is involved in central nervous system controls of feeding and energy balance. Malonyl-CoA, an intermediate of fatty acid biosynthesis, is emerging as a significant player in these processes. Notably, hypothalamic malonyl-CoA has been implicated in leptin's fee...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Gao, Su, Keung, Wendy, Serra, Dolors, Wang, Wei, Carrasco, Patricia, Casals, Nuria, Hegardt, Fausto G., Moran, Timothy H., Lopaschuk, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747894/
https://ncbi.nlm.nih.gov/pubmed/21508288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00092.2011
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