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Hypothalamic malonyl-CoA as a mediator of feeding behavior

Previous studies showed that i.p. administration of C75, a potent inhibitor of fatty acid synthase (FAS), blocked fasting-induced up-regulation of orexigenic neuropeptides and down-regulation of anorexigenic neuropeptides in the hypothalami of mice. As a result, food intake and body weight were dras...

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Detalhes bibliográficos
Main Authors: Hu, Zhiyuan, Cha, Seung Hun, Chohnan, Shigeru, Lane, M. Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC240668/
https://ncbi.nlm.nih.gov/pubmed/14532332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834402100
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