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Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle

Malonyl-CoA functions as a mediator in the hypothalamic sensing of energy balance and regulates the neural physiology that governs feeding behavior and energy expenditure. The central administration of C75, a potent inhibitor of the fatty acid synthase (FAS), increases malonyl-CoA concentration in t...

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Detalhes bibliográficos
Main Authors: Cha, Seung Hun, Hu, Zhiyuan, Chohnan, Shigeru, Lane, M. Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253598/
https://ncbi.nlm.nih.gov/pubmed/16203972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507300102
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