Hypothalamic Ceramide Levels Regulated by CPT1C Mediate the Orexigenic Effect of Ghrelin

Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase pathway, leading to a decline in malonyl-CoA levels and desinhibition of carnitine palmitoyltransferase 1A (CPT1A), which increases mitochondrial fatty acid oxidation and ult...

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Detalhes bibliográficos
Main Authors: Ramírez, Sara, Martins, Luís, Jacas, Jordi, Carrasco, Patricia, Pozo, Macarena, Clotet, Josep, Serra, Dolors, Hegardt, Fausto G., Diéguez, Carlos, López, Miguel, Casals, Núria
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712075/
https://ncbi.nlm.nih.gov/pubmed/23493572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1451
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